APPENDIX 4

Autores: Sociedad Argentina de Reumatología

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Evidence synthesis for 20 topics of general interest related to the treatment of rheumatoid arthritis:
1) treatment implications in preclinical rheumatoid arthritis;
2) early rheumatoid arthritis;
3) window of opportunity in rheumatoid arthritis;
4) difficult-to-treat rheumatoid arthritis;
5) poor prognostic factors in rheumatoid arthritis;
6) concept of sustained remission in rheumatoid arthritis;
7) usefulness of joint ultrasound for the diagnosis and follow-up of rheumatoid arthritis;
8) low-dose glucocorticoids in rheumatoid arthritis;
9) short-term glucocorticoids in rheumatoid arthritis;
10) pregnancy and rheumatoid arthritis;
11) breastfeeding and rheumatoid arthritis;
12) obesity and rheumatoid arthritis;
13) diabetes and rheumatoid arthritis;
14) heart failure and rheumatoid arthritis;
15) hepatitis B and rheumatoid arthritis;
16) cancer and rheumatoid arthritis;
17) HIV and rheumatoid arthritis;
18) oral hygiene and rheumatoid arthritis;
19) effect of smoking cessation on rheumatoid arthritis;
20) treatment reduction and discontinuation in rheumatoid arthritis.