A comparative study between seronegative rheumatoid arthritis and polyarticular psoriatic arthritis: cross-sectional report in a Brazilian cohort

Autores: Annelise Perachi Costodio, Letícia Mariussi Legramanti, Ana Paula Beckhauser, Barbara S. Kahlow, Renato Nisihara, Thelma Skare

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Objectives: the study compared seronegative RA and polyarticular psoriatic arthritis (APs) in terms of cardiovascular risk, quality of life, depression, and functionality.

Materials and methods: data from 45 patients with seronegative RA and 36 with polyarticular APs were analyzed. Questionnaires were used to assess depression (CES-D), functionality (Health Assessment Questionnaire-HAQ), and quality of life (SF-12). Carotid intima-media thickness (cIMT) was measured to assess cardiovas-cular risk.

Results: the results showed similar rates of hypertension, diabetes, and dyslipidemia between both groups. However, patients with APs had higher BMI and abdominal circumference. cIMT was equivalent between groups. Depression and quality of life did not show significant differences. Patients with RA presented worse functionality, according to the HAQ.

Conclusions: in our cohort, patients with RA and seronegative APs had similarities in quality of life, depression, and cardiovascular risk, except for differences in BMI and abdominal circumference, which were higher in APs. Functionality was worse in AR compared to APs.